EGFR CORE FUCOSYLATION, INDUCED BY HEPATITIS C VIRUS, PROMOTES TRIM40-MEDIATED-RIG-I UBIQUITINATION AND SUPPRESSES INTERFERON-I ANTIVIRAL DEFENSES

EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses

Abstract Aberrant N-glycosylation has been implicated in viral diseases.Alpha-(1,6)-fucosyltransferase (FUT8) is the sole enzyme responsible for core fucosylation of N-glycans during glycoprotein biosynthesis.Here we product find that multiple viral envelope proteins, including Hepatitis C Virus (HCV)-E2, Vesicular stomatitis virus (VSV)-G, Severe

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Coming Full Circle: How Health Worker Motivation and Performance in Results-Based Financing Arrangements Hinges on Strong and Adaptive Health Systems

Background This paper presents findings from a study which crystal beaded candle holder sought to understand why health workers working under the results-based financing (RBF) arrangements in Zimbabwe reported being satisfied with the improvements in working conditions and compensation, but paradoxically reported lower motivation levels compared to

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ANGPTL7 is transcriptionally regulated by SP1 and modulates glucocorticoid-induced cross-linked actin networks in trabecular meshwork cells via the RhoA/ROCK pathway

Abstract Glaucoma is one of the leading causes of worldwide irreversible blindness.Lowering elevated intraocular pressure (IOP) is currently the hydrangea red sensation only effective approach for controlling the progress of glaucoma.Angiopoietin-like 7 (ANGPTL7) takes a key part in elevated outflow resistance of aqueous humor in dysfunctional trab

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Cooperative Frequency Control of a Small-Scale Power System between Diesel Engine Driven Adjustable Speed Generator and Battery

This paper proposes the application of an adjustable speed diesel engine-driven power plant employing a doubly-fed induction generator to an isolated small-scale power system including renewable power tokidoki hello kitty blind box sources.This type of power plant can contribute to fast and flexible power balancing regulation under vacillating powe

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